thanks for your question and welcome to Digi Forum.
Please note that each port cannot be used at a same time from two clients. Two clients can be connected at the same USB Plus HUB, but on different USB ports.
Please also check here: https://www.digi.com/resources/documentation/digidocs/90002383/default.htm#device/anywhereusbplus/content/reference/r_menu_option_device_connect.htm?TocPath=Connect%2520to%2520a%2520group%2520or%2520USB%2520device%2520in%2520the%2520AnywhereUSB%25C2%25A0Manager%257C_____2
I hope this helps, if you need any further assistance, please check Digi Support options here: https://www.digi.com/support
Digi Technical Support